The conferences will begin at 9:00 am on June 6, 2018 and will end at 15:30 pm on June 8, 2018.
The excursion and gala dinner will take place on the afternoon and evening of June 7, 2018 – Parc du Futuroscope
Wednesday June 6, 2018 Sessions A and B
8:00 – 9:00 REGISTRATION
9:00 – 9:20 Welcome talk: Pr. Jean-Marc Berjeaud, University of Poitiers, France and Pr Yves Jean, President of the University of Poitiers, France
9:20 – 10:00 Opening lecture: Pr. Wilfred A. van der Donk, University of Illinois, USA
Biosynthesis and Engineering of Cyclic Peptide Antibiotics.
10:00 – 12:20 SESSION A: Discovery of novel antimicrobial peptides (biodiversity, data-mining, synthetic and recombinant peptides). Co-chairs: Pr. Alain Dufour and Dr. Roderich D. Süssmuth
10:00 – 10:30 Keynote lecture: Pr. Monique L. van Hoek, George Mason University, USA
Diversity in Host Defense Antimicrobial Peptides.
10:30 – 11:00 Coffee break and POSTER SESSION
11:00 – 11:20 Mian Chee Gor, Griffith University, Australia: Structural and genetic characterisation of a novel circular bacteriocin, plantacyclin B21AG, from Lactobacillus plantarum B21.
11:20 – 11:40 Margot Schlusselhuber, University of Rouen Normandy, France: Antimicrobial potential of cyclic lipopeptide Milkisin, a new member of amphisin family.
11:40 – 12:00 Leslie Hicks, University of North Carolina, USA: PepSAVI-MS for natural product bioactive peptide discovery.
12:00 – 12:20 Albane Jouault, University of Bretagne-Sud, France: The alterocin gene encodes an antibiofilm protein secreted by the marine bacterium Pseudoalteromonas sp. 3J6.
12:20 – 13:50 LUNCH
13:50 – 14:40 SESSION A: Discovery of novel antimicrobial peptides (biodiversity, data-mining, synthetic and recombinant peptides). Co-chairs: Pr. Djamel Drider and Dr. Vincent Delafont
13:50 – 14:10 Sjoerd B. van der Meulen, University of Groningen, The Netherlands: Heterologous expression and modification of antimicrobial peptides from eukaryotes in Lactococcus lactis.
14:10 – 14:40 Keynote lecture: Pr. Roderich D. Süssmuth, Technical University Berlin, Germany
Ribosomal and Non-ribosomal Peptides from Bacteria and Fungi – Structural and Biosynthetic Aspects.
14:40 – 16:40 SESSION B: Interactions between antimicrobial peptides and microbiotas. Co-chairs: Dr. Alexandre Crépin and Pr. Olivier Lesouhaitier
14:40 – 15:10 Keynote lecture: Dr. Abdelaziz Heddi, INSA Lyon, France
The bacteriome immunity controles endosymbionts and promotes host homeostasis.
15:10 – 15:30 Joy Lachat, University of Paris-Sud, France: Genes required for antimicrobial peptide-resistance and symbiosis identified by Tn-seq in the Burkholderia symbiont of the insect Riptortus pedestris.
15:30 – 15:50 Anjali Priya, Indian Institute of Technology, New Delhi, India: Cell Penetrating Peptides as Antimicrobials: Therapeutics for Tuberculosis Management.
15:50 – 16:10 Hasna Boubakri, University of Lyon 1, France: Alnus glutinosa upregulated peptides: effects on its bacterial symbiont Frankia.
16:10 – 16:40 Coffee break and POSTER SESSION
16:40 – 17:50 SESSION B: Interactions between Antimicrobial peptides and Microbiotas. Co-chairs : Dr. Julien Diana and Dr. Abdelaziz Heddi
16:40 – 17:00 Daniel Oyanedel-Trigo, University of Montpellier, France: Surface determinants of vibrios contributing to resistance to host cellular and molecular defenses.
17:00 – 17:20 Sylvie Rebuffat, Sorbonne University, France: A lasso peptide in the intestinal tract: Stability and effects on the microbiota and on the pathogen Salmonella.
17:20 – 17:50 Keynote lecture: Pr. Olivier Lesouhaitier, University of Rouen, France
Neuropeptides and bacterial interactions: The example of the impact of the C-type natriuretic peptide (CNP) on Pseudomonas aeruginosa biofilm formation.
Thursday June 7, 2018 Sessions C and D
8:30 – 10:30 SESSION C: Biosynthesis of antimicrobial peptides and mechanisms of antimicrobial activity. Co-chairs: Pr. Sylvie Rebuffat and Pr. Wilfred A. van der Donk
8:30 – 9:00 Keynote lecture: Dr. Konstantin Severinov, Skolkovo Institute of Science and Technology, Russia
The expanding family of Microcin C-like peptide-nucleotite Trojan-horse inhibitors of protein synthesis.
9:00 – 9:20 Luca Dalponte, University of Aberdeen, UK: Expanding the diversity of cyclic peptide libraries by chemoenzymatic C- and N-prenylation.
9:20 – 9:40 Thomas Aumer, IAB – Grenoble Alpes University, France: Study of the mechanism of action of an antifungal peptide to control the phytopathogenic fungus Botrytis cinerea.
9:40 – 10:00 Niels Geudens, Ghent University, Belgium: Membrane Interactions of Cyclic Lipodepsipeptides.
10:00 – 10:30 Coffee break and POSTER SESSION
10:30 – 11:40 SESSION C: Biosynthesis of antimicrobial peptides and mechanisms of antimicrobial activity. Co-chairs: Dr. Sophie Sablé and Dr. Julien Verdon
10:30 – 10:50 Jazmin Meza Torres, Pasteur Institute, France: Characterization of LLS: a newbacteriocin from Listeria monocytogenes epidemic strains.
10:50 – 11:10 Kaori Sugihara, University of Geneva, Switzerland: Synergistic effect between human alpha defensin and LL37 characterized by technique in physical chemistry.
11:10 – 11:40 Keynote lecture: Dr. Eefjan Breukink , Utrecht University, The Netherlands
Mechanisms of action of lantibiotics: how we can learn from nature to fight bacteria.
11:40 – 12:30 SESSION D: Immune modulation and other functions of antimicrobial peptides. Co-chairs: Dr. Anne-Christine Lalmanach and Pr. Günther Weber
11:40 – 12:10 Keynote lecture: Dr. Julien Diana, Necker Institute, France
Exploring the regulatory roles of antimicrobial peptides on beta-cell function and the immune system: implication for future therapy against type 1 diabetes.
12:10 – 12:30 Mark Hanson, Global Health Institute, Switzerland: Systematic functional analysis of Drosophila antimicrobial peptides using CRISPR/CAS9 mutants.
12:30 – 14:00 LUNCH
14:00 – 15:30 SESSION D: Immune modulation and other functions of antimicrobial peptides. Co-chairs: Pr. Christine Braquart-Varnier and Dr. Joshy Jacob
14:00 – 14:20 Céline Chessa, University of Poitiers, France: Effects of antimicrobial peptides produced by human keratinocytes during West Nile virus infection.
14:20 – 14:40 Anne-Christine Lalmanach, University of Tours, France: Assessment of anti-viral activity of avian defensins.
14:40 – 15:00 Maaike Scheenstra, Utrecht University, The Netherlands: Cathelicidins have their own unique fingerprint for antimicrobial and immunomodulatory activity.
15:00 – 15:30 Keynote lecture: Pr. Günther Weber, University of Tours, France
LL-37: Jack-of-all-trades with an unusual trick?
16:00 Departure for excursion and Gala dinner at the Futuroscope Park
Friday June 8, 2018 Session E
08:30 – 10:30 SESSION E: Resistance to antimicrobial peptides and therapeutic applications. Co-chairs: Pr. Marie-Hélène Rodier and Dr. Philippe Bulet
8:30 – 9:00 Keynote lecture: Dr. Birgitta Agerberth, Karolinska Institute, Sweden
Induction of Innate Antimicrobial Peptides as a Strategy for Host-Directed Therapy against Infections.
9:00 – 9:20 Des Field, University College Cork, Ireland: Nisin PV; a bioengineered derivative resistant to the Nisin Resistance Protein.
9:20 – 9:40 Vincent Humblot, Sorbonne University, France: Site-Specific Grafting on Titanium Surfaces with Hybrid Temporin Antibacterial Peptides.
9:40 – 10:00 Balint Kintses, BRC of the Hungarian Academy of Sciences, Hungary: Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiome.
10:00 – 10:30 Coffee break and POSTER SESSION
10:30 – 10:50 GENEPEP Society: Company presentation.
10:50 – 12:00 SESSION E: Resistance to antimicrobial peptides and therapeutic applications. Co-chairs: Pr. Jean-Marc Berjeaud and Dr. Vincent Humblot
10:50 – 11:10 Marie-Laure Jourdain, Reims-Champagne-Ardenne University, France: Antimicrobial peptides (AMPs) gene expression in chronic periodontitis patients; a clinical pilot study.
11:10 – 11:30 Wang Xiumin, Chinese Academy of Agricultural Sciences, China: Improved antibacterial and anti-inflammatory activities of chimeric peptides by connecting LBP-14 and a marine peptide-N6 via non-cleavable linkers.
11:30 – 12:00 Keynote lecture: Dr. Joshy Jacob, Emory University, USA
An amphibian host defense peptide is virucidal for Zika and Dengue viruses.
12:00 – 13:30 LUNCH
13:30 – 14:00 AWARDS (Best poster prices)
14:00 – 14:40 Closing lecture: Dr. Paul D. Cotter, APC Microbiome Institute, Cork, Ireland
Harnessing the Gut Microbiota for Bacteriocin Research.
14:40 – 15:00 CONCLUDING REMARKS: Pr. Jean-Marc Berjeaud, University of Poitiers, France
15:00 – 15:30 Coffee break