The conferences will begin at 9:00 am on June 6, 2018 and will end at 15:30 pm on June 8, 2018.
The excursion and gala dinner will take place on the afternoon and evening of June 7, 2018 – Parc du Futuroscope


Wednesday June 6, 2018                          Sessions A and B


8:00 – 9:00              REGISTRATION

9:00 – 9:20              Welcome talk: Pr. Jean-Marc Berjeaud, University of Poitiers, France and Pr Yves Jean, President of the University of Poitiers, France

9:20 – 10:00            Opening lecture: Pr. Wilfred A. van der Donk, University of Illinois, USA

Biosynthesis and Engineering of Cyclic Peptide Antibiotics.

10:00 – 12:20         SESSION A: Discovery of novel antimicrobial peptides  (biodiversity, data-mining, synthetic and recombinant peptides). Co-chairs: Pr. Alain Dufour and Dr. Roderich D. Süssmuth

10:00 – 10:30     Keynote lecture: Pr. Monique L. van Hoek, George Mason University, USA

Diversity in Host Defense Antimicrobial Peptides.

10:30 – 11:00     Coffee break and POSTER SESSION

11:00 – 11:20     Mian Chee Gor, Griffith University, Australia: Structural and genetic characterisation of a novel circular bacteriocin, plantacyclin B21AG, from Lactobacillus plantarum B21.

11:20 – 11:40     Margot Schlusselhuber, University of Rouen Normandy, France: Antimicrobial potential of cyclic lipopeptide Milkisin, a new member of amphisin family.

11:40 – 12:00     Leslie Hicks, University of North Carolina, USA: PepSAVI-MS for natural product bioactive peptide discovery.

12:00 – 12:20     Albane Jouault, University of Bretagne-Sud, France: The alterocin gene encodes an antibiofilm protein secreted by the marine bacterium Pseudoalteromonas sp. 3J6.

12:20 – 13:50         LUNCH

13:50 – 14:40         SESSION A: Discovery of novel antimicrobial peptides (biodiversity, data-mining, synthetic and recombinant peptides). Co-chairs: Pr. Djamel Drider and Dr. Vincent Delafont

13:50 – 14:10     Sjoerd B. van der Meulen, University of Groningen, The Netherlands: Heterologous expression and modification of antimicrobial peptides from eukaryotes in Lactococcus lactis.

14:10 – 14:40     Keynote lecture: Pr. Roderich D. Süssmuth, Technical University Berlin, Germany

Ribosomal and Non-ribosomal Peptides from Bacteria and Fungi – Structural and Biosynthetic Aspects.

14:40 – 16:40         SESSION B: Interactions between antimicrobial peptides and microbiotas. Co-chairs: Dr. Alexandre Crépin and Pr. Olivier Lesouhaitier

14:40 – 15:10     Keynote lecture: Dr. Abdelaziz Heddi, INSA Lyon, France

The bacteriome immunity controles endosymbionts and promotes host homeostasis.

15:10 – 15:30     Joy Lachat, University of Paris-Sud, France: Genes required for antimicrobial peptide-resistance and symbiosis identified by Tn-seq in the Burkholderia symbiont of the insect Riptortus pedestris.

15:30 – 15:50     Anjali Priya, Indian Institute of Technology, New Delhi, India: Cell Penetrating Peptides as Antimicrobials: Therapeutics for Tuberculosis Management.

15:50 – 16:10     Hasna Boubakri, University of Lyon 1, France: Alnus glutinosa upregulated peptides: effects on its bacterial symbiont Frankia.

16:10 – 16:40     Coffee break and POSTER SESSION

16:40 – 17:50         SESSION B: Interactions between Antimicrobial peptides and Microbiotas. Co-chairs : Dr. Julien Diana and Dr. Abdelaziz Heddi

16:40 – 17:00     Daniel Oyanedel-Trigo, University of Montpellier, France: Surface determinants of vibrios contributing to resistance to host cellular and molecular defenses.

17:00 – 17:20     Sylvie Rebuffat, Sorbonne University, France: A lasso peptide in the intestinal tract: Stability and effects on the microbiota and on the pathogen Salmonella.

17:20 – 17:50     Keynote lecture: Pr. Olivier Lesouhaitier, University of Rouen, France

Neuropeptides and bacterial interactions: The example of the impact of the C-type natriuretic peptide (CNP) on Pseudomonas aeruginosa biofilm formation.


Thursday June 7, 2018                              Sessions C and D


8:30 – 10:30         SESSION C: Biosynthesis of antimicrobial peptides and mechanisms of antimicrobial activity. Co-chairs: Pr. Sylvie Rebuffat and Pr. Wilfred A. van der Donk

8:30 – 9:00          Keynote lecture: Dr. Konstantin Severinov, Skolkovo Institute of Science and Technology, Russia

The expanding family of Microcin C-like peptide-nucleotite Trojan-horse inhibitors of protein synthesis.

9:00 – 9:20          Luca Dalponte, University of Aberdeen, UK: Expanding the diversity of cyclic peptide libraries by chemoenzymatic C- and N-prenylation.

9:20 – 9:40          Thomas Aumer, IAB – Grenoble Alpes University, France: Study of the mechanism of action of an antifungal peptide to control the phytopathogenic fungus Botrytis cinerea.

9:40 – 10:00        Niels Geudens, Ghent University, Belgium: Membrane Interactions of Cyclic Lipodepsipeptides.

10:00 – 10:30     Coffee break and POSTER SESSION

10:30 – 11:40         SESSION C: Biosynthesis of antimicrobial peptides and mechanisms of antimicrobial activity. Co-chairs: Dr. Sophie Sablé and Dr. Julien Verdon

10:30 – 10:50     Jazmin Meza Torres, Pasteur Institute, France: Characterization of LLS: a newbacteriocin from Listeria monocytogenes epidemic strains.

10:50 – 11:10     Kaori Sugihara, University of Geneva, Switzerland: Synergistic effect between human alpha defensin and LL37 characterized by technique in physical chemistry.

11:10 – 11:40     Keynote lecture: Dr. Eefjan Breukink , Utrecht University, The Netherlands

Mechanisms of action of lantibiotics: how we can learn from nature to fight bacteria.

11:40 – 12:30         SESSION D: Immune modulation and other functions of antimicrobial peptides. Co-chairs: Dr. Anne-Christine Lalmanach and Pr. Günther Weber

11:40 – 12:10     Keynote lecture: Dr. Julien Diana, Necker Institute, France

Exploring the regulatory roles of antimicrobial peptides on beta-cell function and the immune system: implication for future therapy against type 1 diabetes.

12:10 – 12:30     Mark Hanson, Global Health Institute, Switzerland: Systematic functional analysis of Drosophila antimicrobial peptides using CRISPR/CAS9 mutants.

12:30 – 14:00         LUNCH

14:00 – 15:30         SESSION D: Immune modulation and other functions of antimicrobial peptides.  Co-chairs: Pr. Christine Braquart-Varnier and Dr. Joshy Jacob

14:00 – 14:20     Céline Chessa, University of Poitiers, France: Effects of antimicrobial peptides produced by human keratinocytes during West Nile virus infection.

14:20 – 14:40     Anne-Christine Lalmanach, University of Tours, France: Assessment of anti-viral activity of avian defensins.

14:40 – 15:00     Maaike Scheenstra, Utrecht University, The Netherlands: Cathelicidins have their own unique fingerprint for antimicrobial and immunomodulatory activity.

15:00 – 15:30     Keynote lecture: Pr. Günther Weber, University of Tours, France

LL-37: Jack-of-all-trades with an unusual trick?

16:00                         Departure for excursion and Gala dinner at the Futuroscope Park


Friday June 8, 2018                                     Session E


08:30 – 10:30         SESSION E: Resistance to antimicrobial peptides and therapeutic applications. Co-chairs: Pr. Marie-Hélène Rodier and Dr. Philippe Bulet

8:30 – 9:00          Keynote lecture: Dr. Birgitta Agerberth, Karolinska Institute, Sweden

Induction of Innate Antimicrobial Peptides as a Strategy for Host-Directed Therapy against Infections.

9:00 – 9:20          Des Field, University College Cork, Ireland: Nisin PV; a bioengineered derivative resistant to the Nisin Resistance Protein.

9:20 – 9:40          Vincent Humblot, Sorbonne University, France: Site-Specific Grafting on Titanium Surfaces with Hybrid Temporin Antibacterial Peptides.

9:40 – 10:00        Balint Kintses, BRC of the Hungarian Academy of Sciences, Hungary: Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiome.

10:00 – 10:30     Coffee break and POSTER SESSION

10:30 – 10:50         GENEPEP Society: Company presentation.

10:50 – 12:00         SESSION E: Resistance to antimicrobial peptides and therapeutic applications.  Co-chairs: Pr. Jean-Marc Berjeaud and Dr. Vincent Humblot

10:50 – 11:10     Marie-Laure Jourdain, Reims-Champagne-Ardenne University, France: Antimicrobial peptides (AMPs) gene expression in chronic periodontitis patients; a clinical pilot study.

11:10 – 11:30     Wang Xiumin, Chinese Academy of Agricultural Sciences, China: Improved antibacterial and anti-inflammatory activities of chimeric peptides by connecting LBP-14 and a marine peptide-N6 via non-cleavable linkers.

11:30 – 12:00     Keynote lecture: Dr. Joshy Jacob, Emory University, USA

An amphibian host defense peptide is virucidal for Zika and Dengue viruses.

12:00 – 13:30         LUNCH

13:30 – 14:00         AWARDS (Best poster prices)

14:00 – 14:40         Closing lecture: Dr. Paul D. Cotter, APC Microbiome Institute, Cork, Ireland

Harnessing the Gut Microbiota for Bacteriocin Research.

14:40 – 15:00         CONCLUDING REMARKS: Pr. Jean-Marc Berjeaud, University of Poitiers, France

15:00 – 15:30         Coffee break